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Single Shot at Doctor’s Office May Be Future of HIV Prevention

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Truvada, the other “little blue pill,” is taken daily to prevent HIV and has been touted as a miracle drug responsible for lowering HIV rates across the United States. But soon, the daily pill may be overshadowed by an even simpler method—a single flu shot-like injection at the doctor’s office, once every two months.

The National Institutes of Health (NIH) announced last week that it was entering the first-ever global clinical trial of an injectable HIV-prevention drug called cabotegravir. The trial is taking place in eight countries across three world regions—the Americas, Africa and Asia—and researchers are enrolling 4,500 gay and bisexual men along with transgender women, pulling from groups with the highest rates of new infections.

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Image: Colorized electron microscope image of the HIV virus.HIV, the virus that causes AIDS BSIP/UIG Via Getty Images

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http://www.nbcnews.com/feature/nbc-out/single-shot-doctor-s-office-may-be-future-hiv-prevention-n700916

Exciting Antibody Discovery Sparks New Hope For Future HIV Vaccine

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THE HUFFINGTON POST

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Scientists have discovered an antibody that can powerfully neutralize many variants of the most common strain of HIV, opening up a door for researchers to explore treatment and prevention options for the potentially fatal virus. 

Antibodies ― proteins created by our immune system that are in charge of spotting and neutralizing potentially harmful substances in our body ― are promising avenues for potential vaccines and treatments against the virus. 

The new antibody, named N6, was isolated from the blood of a person with HIV. It managed to neutralize 98 percent of the HIV variants that researchers tested it on, including 16 out of 20 variants that are usually resistant to this kind of antibody protein.

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Álex Cámara via Getty Images
An antibody called N6 could theoretically help protect people against most HIV infections.

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http://www.huffingtonpost.com/entry/antibody-future-hiv-vaccine_us_582cfd76e4b030997bbd7963

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Surgeons Have Completed the First HIV-Positive Organ Transplants — Here’s Why It Matters

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~~~~MicScience1

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Every year, around 17,000 kidney transplants and 6,000 liver transplants are performed in the U.S. But there was something special about two recent kidney and liver transplants performed at Johns Hopkins University Medical Center.

The kidney and liver came from a deceased donor with HIV, and they were transplanted into patients who also have HIV. They’re the first HIV-positive organ transplants since the 2013 repeal of an outdated law banning people with HIV from donating their organs.

“This is an unbelievably exciting day for our hospital and our team, but more importantly, for patients living with both HIV and end-stage organ disease,” Dr. Dorry L. Segev, professor of surgery at the Johns Hopkins University School of Medicine, said in a statement. 

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Surgeons Have Completed the First HIV-Positive Organ Transplants — Here's Why It Matters

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With Big Pharma Support, Human Gene Editing Could Be Closer Than We Thought

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~~~~MicTech1

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Here’s how you know CRISPR, the revolutionary gene-editing technology getting all kinds of hype around the web, is poised to go mainstream: Big Pharma’s getting in the game.

It was recently announced that a $300 million joint venture between Bayer AG (best known for its aspirin) and bio startup CRISPR Therapeutics will aim to develop drugs for blindness, blood disorders and congenital heart disease. It’s a logical next step, especially since scientists at a Los Angeles-based medical institute recently proved they could use CRISPR/Cas9 to treat a type of inheritable blindness in mice.

For a little background, CRISPR/Cas9 gives scientists the ability to directly modify or correct changes in our genome, especially ones that come from disease, by “cutting” the genes with a protein called Cas9, which you might call the scissors. When CRISPR is successful, it means that we can change a busted protein — like one from cancer or HIV — and fully correct the problem.

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!!!!!BigPharma1Image Credit: Getty Images

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http://mic.com/articles/132506/with-big-pharma-support-for-crispr-were-closer-to-human-gene-editing-than-we-thought#.UvrsrYQ5W

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Second baby possibly ‘cured’ of HIV

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~~~~CNNHealth1
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The first time, it happened almost by accident.

Just hours after delivery, a baby born with HIV in Mississippi was given high doses of three antiretroviral drugs. More than three years later, doctors say the little girl has no evidence of the life-threatening disease in her blood, despite being off medication for nearly two years.

Now doctors say another child born with the virus appears to be free of HIV after receiving similar treatment. The case report was presented at the annual Conference on Retroviruses and Opportunistic Infections in Boston this week.

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Doctors say a second child born with HIV appears to be virus-free after antiretroviral treatment.
Doctors say a second child born with HIV appears to be virus-free after antiretroviral treatment.
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Early HIV drugs ‘functionally cure about one in 10’

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~~~~BBCNewsHealth1

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Rapid treatment after HIV infection may be enough to “functionally cure” about a 10th of those diagnosed early, say researchers in France.

They have been analysing 14 people who stopped therapy, but have since shown no signs of the virus resurging.

It follows reports of a baby girl being effectively cured after very early treatment in the US.

However, most people infected with HIV do not find out until the virus has fully infiltrated the body.

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HIV Prevention: Nobel Laureate David Baltimore Talks VIP, New Developments (VIDEO)

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Researchers may have discovered a way to protect against the transmission of HIV–a worldwide epidemic that now infects about 35 million people.

Nobel Laureate Dr. David Baltimore and colleagues at his Caltech lab are injecting mice with a powerful prophylaxis called VIP. And guess what? It works. Caltech postdoctoral fellow Alex Balazs is heading up this groundbreaking research. So is it now time to test this approach in humans?

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End of AIDS in sight says UN report as new HIV infections continue to fall

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Moara de Vânt

Să facem glume, nu război

🇲🇲Dear all peace-loving people around the world🇲🇲

In the world, human beings are facing various problems. People who are full of greed, anger, and ignorance are seen to be fighting with each other in words and deeds. As the fighting continues, various problems such as civil wars, wars of aggression, and wars of aggression are occurring. As world peace is being destroyed, humans are facing unbearable problems. Innocent children and women are not getting the rights they deserve and deserve. I can't think of one thing every time. What is it? The United Nations. If we look at the responsibilities and duties of the United Nations, I think it is not suitable for solving the problems that are happening in the world today. In fact, the United Nations and the World Security Council, such an organization must rule the world, must be able to give orders, and must have various ways to obey orders. There must be no organization that can influence more than that organization. There should be experts from each country. They can even dominate the superpowers like the US, China, and Britain. Only then will global peace be achieved quickly. Now, if a country with power develops more militarily, economically, or socially than its own country, then powerful countries will jealously seek out enemies and wage war. Or they will attack with fighter jets. In this, innocent people are losing their lives. No one understands the value of a life. You should think about how to achieve global peace by controlling these. If the US continues to be the permanent president of the UN, world peace will never be achieved. If you think carefully, no one sees that they are working for the common good, but for their own benefit, for the benefit of their own country. The permanent president of the UN and the Security Council has rejected this, As a young Rohingya, I have come to realize that only by electing the president and secretary from among the countries in the world through a secret ballot system and governing the world fairly can we achieve global peace. The United Nations and the Security Council are organizations in which any country must govern, give orders, and make them obey their orders. For example, only when a defendant is tried in court can we hold the leaders of the countries in check and control them, can we achieve global peace smoothly. Otherwise, it will not be easy for powerful countries to use various excuses to end this war every year, every year, for the benefit of themselves and their countries. No country's leaders pay any attention to the words of the United Nations and the Security Council. If we look at it in practice, look at the Rohingya issue. Myanmar is a small country. Even that country has been under siege for 8 years. What action can be taken? Why is the UN and the Security Council Powerless? Without such Power, how can the organization bring about global peace? Everyone should think about it. Whether there is a veto or a strong one, all countries in the world can only achieve global peace if they are subject to the UN and the Security Council. Seek peace in the quiet embrace of nature. Peace is an indispensable need of the human race. It is not as if one person can kill another person, and it is as if one country can attack another country, but instead of trying to build peace, we must try to destroy the peace now, and the world is getting hotter and is on the verge of collapse. I especially appeal to all the world experts to urgently try to bring about peace in all parts of the world. Mr, Noor Muhamed Arkhan Rohingya Youth Myanmar

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