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Researchers in Florence, Italy, are opening a centuries-old family tomb in hopes of solving one of the art world’s most pressing mysteries. The tomb in question belongs to the family of Lisa Gherardini, the 16th century Florentine woman thought to have been the face of Leonardo da Vinci’s “Mona Lisa.”

According to NBC, a team of specialists have begun a series of DNA tests on three different skeletons found in an Ursuline convent in Florence. The bones were originally discovered in 2012 and are believed to include the remains of Gherardini, the wife of a merchant who at one point lived across the street from da Vinci.

Now, researchers are turning to the Gherardini family tomb, located in Florence’s Basilica della Santissima Annuziata, where they hope to excavate the skeletons of the supposed muse’s sons. The experts plan on comparing DNA evidence from the convent excavation to the bones in the basilica in order to verify that they indeed have access to Mrs. Gherardini’s remains.

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