May 26, 2013
Mohenjo
Science
amazon, ambystoma mexicanum, aquatic salamander, biology, business, climate, Daily Discovery, Environment, Hotels, huffingtonpost, human-rights, Immune Cells, immune system, Limb Regeneration, monash university, Ocean Science, research, Salamander Regeneration, Salamanders, Salamanders Regrow, Science, Science News, Slideshow, technology, Technology News, travel, vacation, Video, Weird Science
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Salamanders can regrow entire limbs and regenerate parts of major organs, an ability that relies on their immune systems, research now shows.
A study of the axolotl (Ambystoma mexicanum), an aquatic salamander, reveals that immune cells called macrophages are critical in the early stages of regenerating lost limbs. Wiping out these cells permanently prevented regeneration and led to tissue scarring. The findings hint at possible strategies for tissue repair in humans.
“We can look to salamanders as a template of what perfect regeneration looks like,” lead study author James Godwin said in a statement. “We need to know exactly what salamanders do and how they do it well, so we can reverse-engineer that into human therapies,” added Goodwin, of the Australian Regenerative Medicine Institute (ARMI) at Monash University in Melbourne. [Ready for Med School? Test Your Body Smarts]
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The axolotl, an aquatic salamander, can regenerate lost limbs.
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http://www.huffingtonpost.com/2013/05/21/limb-regeneration-salamanders-immune-cells-axolotl_n_3311704.html?ref=topbar
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April 5, 2013
Mohenjo
Medical
amazon, antibodies, attacking HIV, bbc, bbc news, body's immune system, body's own "training manual", business, climate, gaming, Health, HIV mutates, HIV Research, HIV/AIDS, immune system, journal Nature, medicine, Mutants, nature, neutralise huge swathes of HIV mutants, onslaught, patient's immune system, patients develop highly effective antibodies, research, Science, Science News, technology, Technology News, travel, vacation, videogames, www bbc co uk
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The body’s own “training manual” for attacking HIV has been recorded by US scientists and it is hoped it can be used to design vaccines.
HIV mutates in order to survive the onslaught of a patient’s immune system.
However, some patients develop highly effective antibodies that can neutralise huge swathes of HIV mutants.
A North Carolina team analysed the arms race between body and virus, published in the journal Nature, and has shown how these antibodies are made.
When someone is infected with HIV, their body produces antibodies to attack it. But the virus mutates and evades the offensive, so the body produces new antibodies that the virus then evades and the war goes on.
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http://www.bbc.co.uk/news/health-22002455
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March 3, 2013
Mohenjo
Medical
A deadly form of skin cancer, amazon, bbc, bbc news, blood, body's best immune defence, body's immune system, business, Cancer Research UK, form of skin cancer, Health, Hotels, immune defence, immune system, journal of clinical investigation, Journal of Clinical Investigation reports, king s college, King's College London, medicine, melanoma, potential test, research, Science, Science News, skin cancer, technology, Technology News, travel, tumour, tumour cells, UK researchers, vacation, www bbc co uk
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A deadly form of skin cancer is able to fend off the body’s immune system, UK researchers have found.
Analysis of tumour and blood samples shows that melanoma knocks out the body’s best immune defence.
A potential test could work out which patients are likely to respond to treatment, the Journal of Clinical Investigation reports.
Cancer Research UK said the body’s response was a “complex puzzle”.
Previous work from the team at King’s College London showed that while patients with melanoma produced antibodies that could attack tumour cells, the immune system often seemed powerless to stop the cancer progressing.
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http://www.bbc.co.uk/news/health-21635697
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