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Novel Drug Eases Symptoms in Alzheimer’s

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Phase II trial demonstrated modest benefit in reducing cognitive decline in patients with Alzheimer’s disease.

An investigational oral drug targeting adrenergic receptors improved scores on memory tests in patients with Alzheimer’s disease in a phase IIa trial, researchers said.

When given with currently approved Alzheimer’s disease drugs, the agent — called ORM-12741 — improved composite memory test scores by 4 percent after 3 months of twice daily treatment, whereas scores worsened by 33 percent in patients receiving memantine and a placebo pill, according to Juha Rouru, MD, of Orion Pharma in Turku, Finland, and colleagues.

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http://www.everydayhealth.com/alzheimers/0313/novel-drug-eases-symptoms-in-alzheimers.aspx

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Daily To-Dos to Combat Dementia Risk

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Beyond exercise and healthy eating, there are plenty of things you can do while you’re younger to ward off dementia and Alzheimer’s.

Rates of dementia and Alzheimer’s have been on the rise. The Alzheimer’s Association reports that, as of last year, 5.4 million Americans were living with the disease — that’s one in eight seniors — and it’s the sixth leading cause of death in the United States. As rates go up, so too does the concern about our ability to care for growing numbers of people with Alzheimer’s and dementia.

Until a cure for Alzheimer’s is discovered, researchers emphasize precautions younger people can take now that may ward off or delay the chance of developing the disorder. From staying active to eating a healthy diet to just being social, there are a number of moves you can make to minimize your Alzheimer’s and dementia risk.

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