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Mark E. Robson, M.D.I must confess that I am very conflicted about adding to the river of words that have been written about Angelina Jolie’s decision to undergo a risk-reducing (preventive) mastectomy. She made a difficult choice, and has discussed that choice with power and grace, in the hope of helping other women. Both the choice and the disclosure took a lot of courage. Full stop. But the power of her celebrity, and the extensive media coverage of her decision, may wind up making things more difficult for some women with BRCA1 or 2 mutations.
I have been involved in research in this area for 17 years, since shortly after BRCA1 and BRCA2 were discovered, and I honestly have no idea what I would do if I were a woman faced with this decision. Imagine the situation. You go to talk to a health care provider because you have a family history of breast cancer or ovarian cancer. Hopefully, you have genetic counseling (which not everyone gets, although they should), and learn about genetics for an hour or so. If it looks like there’s a meaningful chance that genetic testing could be informative, you then give a blood sample or spit in a tube.
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James' World 2 