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Coastal storm to hammer US East Coast with flooding, wind and erosive surf

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A powerful tropical wind and rainstorm will unfold and bring days of coastal flooding, erosive surf, high winds, and rain from the Carolinas to New England; Some areas may face impacts similar to a major nor’easter or hurricane.

A powerful tropical wind and rainstorm will unfold and bring days of coastal flooding, erosive surf, high winds, and rain from the Carolinas to New England; Some areas may face impacts similar to a major nor’easter or hurricane.

A slow-moving storm is brewing along the Atlantic coast of the United States that will strengthen and unleash wind, rain, and pounding surf from late this week into early next week. AccuWeather meteorologists warn the tropical wind and rainstorm could evolve into a named tropical storm, but it may be more akin to the powerful nor’easters that ramp up along the coastline during the winter months, without the snow. “This will be a damaging storm for some along the Atlantic coast,” AccuWeather Chief On-Air Meteorologist Bernie Rayno said.

AccuWeather meteorologists are referring to the system as a tropical wind and rainstorm to raise awareness of the situation and allow those affected to better prepare.

“The storm will form just off the Florida coast late this week and move northward this weekend to next week,” Rayno added. “As the storm drifts to the north, it will grow stronger each day.”

An extended period of stormy conditions is in store with stiffening winds that will raise seas, erosive surf, and coastal flooding, as well as bring much-needed rain to some areas.

The AccuWeather RealImpact™ Scale for this storm is 1. In this case, the storm will be the equivalent of a hurricane.

“The risk of major coastal impacts is amplified by the storm occurring toward the end of the ‘king tides,’ a time when tides are already running above their historical averages from an astronomical perspective,” AccuWeather Chief Meteorologist Jon Porter said. “There is a high risk this storm will be designated a subtropical (hybrid) storm, which is why we have designated this system as a tropical wind and rainstorm, and have issued an eye path map to raise early awareness ahead of potential National Hurricane Center (NHC) classification,” AccuWeather Lead Hurricane Expert Alex DaSilva said.

“A fully tropical storm gets its energy solely from the ocean, a subtropical or hybrid storm gets its energy from both the ocean and the jet stream or stalled front–We think this will be a hybrid storm as a result,” DaSilva said.

Should the storm’s intensity escalate and this storm is officially named by the NHC, it would be designated as Lorenzo, the next name on the 2025 Atlantic list.

There is the potential for major coastal flooding from North Carolina to New Jersey and Cape Cod.

These conditions will develop from North Carolina to Delmarva from Friday to Saturday and expand northward over New Jersey and the New York City area on Sunday. Barrier island communities and low-lying areas that take on water during a tropical storm or nor’easter will likely flood with this event.

Tides are expected to range from 1-3 feet above normal with an AccuWeather StormMax™ surge of 6 feet.

Offshore, waves will build to 10-20 feet and could grow even higher.

The slow-moving nature of this storm will cause days of coastal erosion due to heavy surf and strong rip currents. The prolonged storm may severely damage some beaches and protective dunes.

“Along the immediate coast, winds are likely to get strong enough with this from southeastern Virginia to Delmarva, New Jersey and southeastern New York and possibly southern New England to lead to tree, power line, and property damage,” AccuWeather Senior Meteorologist Dave Dombek said.

Wind gusts of 40-60 mph will frequent coastal areas from North Carolina to eastern Massachusetts. The AccuWeather Local StormMax™ gust for this storm is 80 mph. A hurricane has winds of 74 mph or greater.

In a worst-case scenario, the storm could evolve to hurricane strength and turn inland over the mid-Atlantic with a zone where a significant storm surge, high winds, and heavy rain occur just to the north of the center.

The heaviest rain, which may lead to urban flooding outside of storm surge problems, will generally be confined to the Interstate 95 corridor on east from North Carolina to Massachusetts. The storm is forecast to bring 2-4 inches of soaking rain in many coastal areas, with higher amounts of 4-8 inches expected in coastal North Carolina. The AccuWeather Local StormMax™ rainfall is 10 inches.

Rainfall will diminish sharply farther west and south of coastal South Carolina.

Although hurricanes have remained hundreds of miles offshore in recent months, they have still contributed to significant beach damage and erosion.

“There have been probably five significant episodes of heavy surf, beach erosion, and coastal flooding since the summer, starting with Erin in mid-August,” Rayno said. Eastern North Carolina has borne the brunt with multiple beachfront homes crashing into the sea as shoreline erosion intensified in recent weeks.

The upcoming weekend is forecast to be vastly different than last weekend along part of the Atlantic coast. Last weekend’s sunshine and warmth in the mid-Atlantic and New England regions marked one of the most delightful stretches of the year. The upcoming weekend, especially the latter part, is shaping up to be very stormy and could be damaging and dangerous for some due to the risk of flooding and enraged seas.

Elsewhere, in the tropical Atlantic, Jerry is forecast to gain strength and become a hurricane in the coming days. It will take a sharply curved track near the northeastern Caribbean islands and most likely steer to the east of Bermuda.

Meanwhile, Subtropical Storm Karen continues to move across the northern Atlantic and is not expected to bring impacts to land.

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AccuWeather’s Geoff Cornish breaks down the weather conditions that are expected to strengthen a coastal storm into a powerful system with destructive coastal flooding from Oct. 10-13.

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Click the link below for the complete article (plus accompanying weather Maps):

https://www.accuweather.com/en/hurricane/coastal-storm-to-hammer-us-east-coast-with-flooding-wind-and-erosive-surf/1823707?partner=push_polygon&utm_source=push_polygon&utm_medium=one_app_push&utm_campaign=article_1823707&inapp=true

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Philadelphia has spent $270k on hundreds of one-way bus tickets to encourage homeless people to leave city

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Philadelphia taxpayers have spent around $270,000 funding a scheme that buys one-way bus tickets for homeless people in an attempt to get them to leave the city.

The Stranded Traveler Assistance program has provided tickets for more than 1,000 people to travel across the country since 2021, according to records reviewed by NBC10, with city officials describing it as “the most efficient program in ending homelessness.”

According to information from the city’s Office of Homeless Services, the program provides travel assistance to “non-residents who find themselves stranded, in crisis situations, in Philadelphia.”

“The aid helps travelers return to communities where they have family or social support and will have a better opportunity to attain self-sufficiency,” the department states.

To get the assistance requires the person’s name, social security number, and the number of adults and children that are traveling. They must also have a place to go at the location they are traveling to.

However, city officials acknowledge that the program is not “fail safe,” as there are no court record or background checks, and no follow up once the individual has boarded the bus.

“They come to us and say, ‘Hey, I’m ready to end my homelessness here in the city,’” Bruce Johnson, the assistant deputy director for the Office of Homeless Services, told NBC10.

“We don’t necessarily check court records and backgrounds as far as us assisting participants,” Johnson told the outlet, adding: “It’s a success once we give them that ticket and they arrive at their new destination site.”

As there is also no follow up on the other end, Johnson admitted that Philadelphia officials cannot be certain that the individuals do not end up homeless again in their new destination.

“No program is a fail-safe program,” he said.

The program has reportedly cost taxpayers $270,000 since July 2021.

In addition, investigations by NCB10 found that half of those using the Stranded Traveler program between 2021 and May 2025 traveled under 750 miles away from Philadelphia – and some return.

The outlet reported that one man, Jose Colon, used the program back in July, only to return to the city several weeks later.

The Independent reached out to Philadelphia’s Office of Homeless Services for comment on whether the service was used to move homeless people out of the city and clarification on the number that return.

A business owner in Santa Monica, California, has been testing his own similar program. John Alle, a real estate advisory business owner and co-founder of the Santa Monica Coalition, launched a no-questions-asked program last week offering free flights home to unhoused people in LA with ID and someone waiting at their destination.

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https://static.independent.co.uk/2025/10/07/17/17/A-general-view-shows-the-Philadelphia-city-skyline-from-Camden-New-Jersey-on-Election-Day-on-Novembe.jpeg?quality=75&width=640&auto=webpThe tickets are designed to help people who find themselves ‘stranded’ in the city to get to places where they have ‘family or social support’ (AFP via Getty Images)

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Click the link below for the complete article:

https://www.independent.co.uk/news/world/americas/philadelphia-bus-tickets-homeless-b2841182.html

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Unknown Soldier

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On Jeopardy the other night, the final question was: “How many steps does the guard take during his walk across the Tomb of the Unknown?”
All three missed it.

Tomb of the Unknown Soldier

1. How many steps does the guard take during his
walk across the Tomb of the Unknown and why?
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21 steps. It alludes to the twenty-one gun salute, which is the highest honor given any military or  foreign dignitary.
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2. How long does he wait after his about face to begin his return walk and why?
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21 seconds for the same reason as above.
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3. Why are his gloves wet?
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His gloves are moistened to prevent his losing his grip on the rifle.
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4. Does he carry his rifle on the same shoulder all the time and if not, why not?
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He carries the rifle on the shoulder away from the tomb. After his march across the path, he executes an about face and moves the rifle to the outside shoulder.
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5. How often are the guards changed?
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Guards are changed every thirty minutes, twenty-four hours a day, 365 days a year.
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6. What are the physical traits of the guard limited to?
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For a person to apply for guard duty at the tomb, he must be between 5′ 10′ and 6′ 2′ tall and his waist size cannot exceed 30.’ Other requirements of the Guard: 
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They must commit 2 years of life to guard the tomb, live in a barracks under the tomb, and cannot drink any alcohol on or off duty for the rest of their lives. 
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They cannot swear in public for the rest of their lives and cannot disgrace the uniform {fighting} or the tomb in any way. After two years, the guard is given a wreath pin that is worn on their lapel signifying they served as guard of the tomb. There are only 400 presently worn.
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The guard must obey these rules for the rest of their lives or give up the wreath pin.
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The shoes are specially made with very thick soles to keep the heat and cold from their feet. There are metal heel plates that extend to the top of the shoe in order to make the loud click as they come to a halt.
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There are no wrinkles, folds or lint on the uniform.
Guards dress for duty in front of a full-length mirror.
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The first six months of duty a guard cannot talk to anyone, nor watch TV.
All off duty time is spent studying the 175 notable people laid to rest in Arlington National Cemetery. A guard must memorize who they are and where they are interred.
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Among the notables are: President Taft, Joe E. Lewis {the boxer} and Medal of Honor recipient Audie Murphy, {the most decorated soldier of WWII} of Hollywood fame.
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Every guard spends five hours a day getting his uniforms ready for guard duty.
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ETERNAL REST GRANT THEM O LORD, AND LET PERPETUAL LIGHT SHINE UPON THEM.
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In 2003 as Hurricane Isabelle was approaching Washington , DC , our US Senate/House took 2 days off with anticipation of the storm. On the ABC evening news, it was reported that because of the dangers from the hurricane, the military members assigned the duty of guarding the Tomb of the Unknown Soldier were given permission to suspend the assignment.
They respectfully declined the offer, ‘No way, Sir!’ Soaked to the skin, marching in the pelting rain of a tropical storm, they said that guarding the Tomb was not just an assignment, it was the highest honor that can be afforded to a serviceperson.
The tomb has been patrolled continuously, 24/7, since 1930.
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God Bless and Keep Them
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I don’t usually suggest that many posts be forwarded, but I’d be very proud if this one reached as many people as possible.
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We can be very proud of our young men and women in the service no matter where they serve.
Duty – Honor – Country
IN GOD WE TRUST — with Herbert F Wieland.

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Can Dogs, Cats and Other Pets Truly Improve Your Health?

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We got our first dog when my oldest son was 10. A friend who was a teacher told me that was a perfect age for a kid to have a pet. “Jake can throw his arms around the dog when he doesn’t feel comfortable hugging you anymore,” he said.

It took a bit for me to get over his reminder that my child was growing up, but I immediately recognized my friend’s insight. A beloved animal can make everything seem better. And most of us believe strongly that our pets make us healthier.

Yet the science of human-animal interaction has found mixed results when it comes to physical and psychological health benefits from pets. Depending on the study, for example, people with pets are either less or more likely to be depressed. Experts say this seesawing probably happens because, for some owners, pets serve as a calming influence and emotional support. But in other cases, the study may include more people who are already struggling mentally and get pets to try to feel better; then, such participants are counted as depressed.

Owning a dog has consistently been associated with higher levels of physical activity, no doubt because of all that walking, which has social benefits, too. One of the very first studies in the field, published in 1980, found that people who had been hospitalized for a heart attack or coronary artery disease were more likely to survive the following year if they had a pet, and the researchers suspected that physical activity from walking dogs was partly responsible, although the results held for other kinds of pets, too. A 2019 analysis of several studies, published in Circulation: Cardiovascular Quality and Outcomes, showed a dramatic result: dog ownership was associated with a 24 percent lower risk of dying. But when other researchers reran the same numbers with more adjustments for confounding variables, that benefit nearly disappeared.“Pets are not a medical intervention; they’re a relationship.” —Jessica Bibbo, gerontologistA history of physical activity is one potential confounder. “You’re more likely to have a dog if you’re already somebody who’s active or wants to be active,” says developmental psychologist Megan Mueller of the Cummings School of Veterinary Medicine at Tufts University. “And then once you have that dog, they probably help motivate you to be more active.”

That’s why much of the latest research aims to get beyond such problems by digging into the nuances of human-animal interactions. “Pets are not a medical intervention; they’re a relationship,” says Jessica Bibbo, a gerontologist at the Benjamin Rose Institute on Aging in Cleveland who studies human-animal interactions. And the quality of that relationship, such as the level of attachment and sense of social support, looks like a much better predictor of positive outcomes than just whether there’s a pet in the home, Mueller says: “We are trying to isolate the factors that can help promote those positive relationships [with pets] so we can help people.”

Carefully randomized controlled trials with therapy animals and laboratory experiments offer some clues. A 2025 study had 43 dog owners perform stressful tasks (such as public speaking) with or without their pets present. Those whose dogs accompanied them showed lower spikes of cortisol, a hormone that rises under stress. Another study of about 90 older adults attending a community center randomly assigned half the people to look after five crickets (yes, crickets!) in cages for eight weeks. All the people received the same advice about maintaining their own health. Those who cared for insects showed some improvement in mental and cognitive health compared with those who didn’t.

For older adults, having a pet to care for adds a sense of purpose, Bibbo says, particularly when health is in decline. As part of their work, Bibbo is trying to build pet care into decisions about health care. People often take better care of themselves so they can also look after a loved animal, Bibbo says.

Some of the positive effects seen in controlled settings—such as reduced cortisol levels and heart rates—probably carry over to having a pet in real life, Mueller says, even though real life is messier. As with human relationships, strong, positive bonds with an animal seem to be some of the things that confer health benefits (although even here, there are mixed results). Certainly, pets provide social and emotional support for many people. There’s a physical component as well from having a cat or dog sit in your lap. As a bonus, pets are viewed as nonjudgmental. “Pets aren’t giving you any tough love,” Mueller says.

For adolescents, that can be especially useful (my friend was right). Pets serve as “a bridge helping young people in their transition to autonomy,” says Mueller, whose work focuses on that age group.

Still, we shouldn’t ask too much. Even therapy animals are there to facilitate, not to fix, Bibbo says. And we can’t expect pets to cure serious mental health issues, Mueller says. “But can having a dog or any pet help us build coping skills that are positive for managing anxiety?” she asks. Mueller thinks it’s very possible.

People emphatically believe pets improve our quality of life, and that belief can affect health indirectly. In 2025, economists used a large British dataset with controlled variables to assess how much more money pet owners thought they would have to earn to get the same life satisfaction that pets gave them. The conclusion: up to $90,000 a year. That’s enough to buy dozens of treadmills or go on many relaxing tropical vacations. Co-author Adelina Gschwandtner of the University of Kent in England says, “Are pets good for us? We were able to answer with a resounding yes.”

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https://static.scientificamerican.com/dam/m/6b518c7df316bb4a/original/sa1025SoH01.jpg?m=1757017592.087&w=900Jay Bendt

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Click the link below for the complete article:

https://www.scientificamerican.com/article/can-dogs-cats-and-other-pets-truly-improve-your-health/?_gl=1*192lv7h*_up*MQ..*_ga*MTQ0ODk0MjQ5LjE3NjAwNzcwODg.*_ga_0P6ZGEWQVE*czE3NjAwNzcwODckbzEkZzAkdDE3NjAwNzcwODckajYwJGwwJGgw

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Is Intensive Parenting Helping or Hurting Kids?

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There are a lot of things to worry about as modern parents, from the impact of social media on our kids, to violence in schools. But some of us may be worrying so much that our parenting style leans toward overprotective, and even stifling.

I’m talking about intensive parenting, a term which dates back to 1996 when a sociologist named Sharon Hays coined “intensive mothering.”

The term, which has been compared to helicopter parenting, was brought into the spotlight recently through some parents on TikTok. “We’re now in a position where we have to figure out if we continue putting all of ourselves into our children to help them become better humans or if we scale it back,” one parent shares in a TikTok video talking about the parenting style.

Raquel Herrero-Arias, PhD, a researcher of kids and parents at the University of Bergen in Norway, recently also spoke of wanting to research this parenting style. She sees intensive parenting as a style where caregivers are potentially doing too much, to the detriment of the entire family.

While intensive parenting can have benefits, including building parent-child bonds through more time spent together, it can also lead to issues when taken too far.

What Does Intensive Parenting Mean?

You may practice intensive parenting if you constantly strive to keep your kids entertained, rarely leave them in the care of others, and advocate for them to the point of not respecting boundaries with teachers and coaches. 

I’ll admit to being guilty of some intensive parenting habits, such as organizing my life around my children, and investing too much of myself into their emotional state, as well as obsessing over whether I handled tricky situations well enough.

Some aspects of intensive parenting take the notion of the child-centered family further, with parents basing their entire sense of well-being upon kids’ successes in life. Parents may even attempt to live vicariously through their kids, and worry, well, intensely about their futures.

Intensive parenting typically also includes parents being heavily involved in a child’s academics, extracurricular activities, and social interactions. They may often also step in to help their kids solve problems or handle challenges.

While putting your kids first isn’t necessarily a bad thing, according to experts, intensive parenting can lead to unhealthy pressures being placed on kids, and parents who aren’t focusing on themselves to the point of leading a dangerously unbalanced life.

What’s Causing Intensive Parenting?

It’s believed parents are turning to an intensive style of child-rearing because raising our families in the modern world is more difficult and therefore requires ramped up supervision. Here’s why.

Social media pressures

Experts say social media is a huge cause of intensive parenting.

“Most of us know, on a cognitive level, that social media is a highlight reel—a small piece of what actually happens,” says Anne Welsh, PhD, a Belmont, Massachusetts-based clinical psychologist and specialist in maternal mental health. “However, that constant exposure to other ways of doing things—seemingly perfect ways—starts to have an impact on us.”

For example, a 2024 Little Sleepies survey found about 73% of moms compares themselves to other parents on social media. And 77% of moms report feeling “mom guilt” because of social media.4

Dr. Welsh reports, “I have seen clients whose mental health and parenting confidence improves significantly when they spend less time on social media.”

Lauren Canonico, LCSW, a New York City-based psychotherapist and adjunct professor at Affirmative Therapy Collective, agrees that social media plays a big role in pressuring parents.

“From showing perfectly-packed lunches to allegedly Montessori-approved activities that require hours of preparation, and presenting these as normal, daily activities, we’ve made parents feel that the baseline must be extraordinary, with no room for deviation or falling short,” she explains.

Rise in parenting expectations

Social media isn’t the only reason parenting today is so demanding. Dr. Welsh believes that overall, the expectations for parents have risen dramatically in recent years. 

“There is an expectation that we are perfectly emotionally regulated, endlessly available, and always present,” she says. “While those might be laudable goals, they also aren’t reality.”

Canonico underscores that for her, there is no question this current moment creates greater difficulty for parents.

“The world we live in is busier, more demanding, and more expensive than any time that has come before,” she says. “We’re expecting the same things from ourselves—possibly more given the pressures for perfection—with far less disposable time and income to get it done than past generations.”

Given these perspectives, it’s easy to see how parents turn to an intensive style to cope with the many seeming-requirements of raising our kids today.

A parent’s own upbringing

Outside of the demands of raising small humans at this unprecedented time, there are other factors that may drive caregivers toward intensive parenting. 

“A common theme I see in parenting styles is a pendulum swing from what came before,” says Canonico. “Gen X-ers and Millennials, the two primary groups raising children right now, both have their own unique generational baggage.”

Gen X-ers were the first latchkey kids, whose parents may have both worked, and therefore, they came home to an empty house, unsupervised, after school.

Meanwhile, as Canonico explains, “Millennials have faced crisis after crisis, often feeling unprotected and unprepared, and relying on over-work and hustle culture as guard against this.”

In her view, both generations are working to prevent their kids from going through their lived experiences. 

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https://www.parents.com/thmb/Abg73lYzFi3JKJ2r_eezImhkgWE=/750x0/filters:no_upscale():max_bytes(150000):strip_icc()/Parents-Intensive-Parenting-6cfeefead77c4dfa8bece785c66aaeb1.jpgPhoto:  Parents/GettyImages/xavierarnau

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Click the link below for the complete article:

https://www.parents.com/is-intensive-parenting-helping-or-hurting-kids-8734276

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I regret belittling men. At 63, I’ve ended up alone

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A few years ago, I went to Italy with my then-boyfriend, James. As we sat tucking into a plate of frutti di mare at a seaside restaurant, I struck up a conversation with the waiter in Italian. While I was enjoying myself, James sat glumly and fiddled awkwardly with his phone. Back in the hotel room, he asked why I had ignored him. By speaking in a language he didn’t understand, he said I had managed to make him feel small. I could see his point. I spent quite a while chatting away, oblivious to how he must be feeling. I then went on to joke that as the Italian speaker, I would order for us – after all he didn’t know what osso buco meant… I was showing off. It wasn’t the first time something like this had happened to me. I have always taken the driving seat, been determined to get the last word, and was too busy with books to master the art of charm.

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https://img-s-msn-com.akamaized.net/tenant/amp/entityid/AA1O4oqf.img?w=800&h=435&q=60&m=2&f=jpgRegret

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Click the link below for the complete article (slideshow):

https://www.msn.com/en-ca/lifestyle/lifestylegeneral/i-regret-belittling-men-at-63-i-ve-ended-up-alone/ss-AA1O4jxM?ocid=hpmsn&cvid=68e6fa97fff8435fbf280d5cef5c9a9d&ei=34#interstitial=1

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Live Updates: N.Y. Attorney General Letitia James Indicted After Trump’s Pressure Campaign

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Here’s the latest.

A prosecutor handpicked by President Trump secured an indictment of New York’s attorney general, Letitia James, on bank fraud and false statement charges in the Eastern District of Virginia on Thursday after the president publicly demanded she be charged.

The five-page indictment accused Ms. James of falsely claiming in loan documents that she would use a home she purchased in Norfolk, Va., as a secondary residence, and using it instead as a rental investment property, allowing her to receive favorable terms that would save her close to $19,000.

Ever since President Trump took office, New York’s attorney general, Letitia James, has been suing his administration to block policies that she says threaten access to health care or violate privacy laws and the Constitution.

Just nine days ago, her office sued the Department of Homeland Security and its head, Kristi Noem, after it diverted millions in antiterrorism funds from the Metropolitan Transportation Authority, which runs New York’s subways, buses, and commuter rails. On Oct. 1, a judge temporarily blocked the transfer of money.

When Letitia James ran for New York attorney general in 2018, one of her promises was to sue Donald Trump. She called him an “illegitimate president.” She suggested that he could be criminally charged with obstruction of justice.

She said that her decision to seek office was largely “about that man in the White House who can’t go a day without threatening our fundamental rights.”

The animosity between Letitia James, New York’s attorney general, and President Trump goes back years, to Mr. Trump’s first term in office. Here is what led to Ms. James’s indictment on Thursday.

Nov. 6, 2018: Speaking to supporters in Brooklyn on the night she was elected attorney general, Ms. James announced to Mr. Trump: “We here in New York — and I, in particular — we are not scared of you.” She promised to shine “a bright light into every dark corner of his real estate dealings, and every dealing, demanding truthfulness at every turn.”

For months, high-ranking officials in the Trump administration have accused several of the president’s enemies of mortgage fraud. The two-count indictment of New York’s attorney general, Letitia James, is the first of those allegations to appear in the form of criminal charges.

The indictment refers to a home Ms. James purchased in Norfolk, Va., in 2020. It accuses her of having said in loan documents that she would use the home as a secondary residence, but instead she used the home as a rental property. That, they say, violated her mortgage agreement — which barred her from renting the property — and allowed her to receive favorable loan terms.

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https://static01.nyt.com/images/2025/10/09/multimedia/live-blog-20251009-trump-news-header-wgvj/live-blog-20251009-trump-news-header-wgvj-jumbo.jpg?quality=75&auto=webp

President Trump demanded publicly that Attorney General Letitia James of New York be charged. Credit…Victor J. Blue for The New York Times

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Click the link below for the complete article:

https://www.nytimes.com/live/2025/10/09/us/trump-news

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Lab-Made Mini Organs Could Transform Female Reproductive Medicine

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In 2017, Ashley Moffett, a reproductive immunologist, walked to the pharmacy near her laboratory at the University of Cambridge, UK, to buy a pregnancy test. But it wasn’t for Moffett. Her postdoc, Margherita Turco, had created what she thought might be the first cluster of cells capable of mimicking the tissue of the placenta — a placental organoid. But she needed a way to be sure.

“We must do a pregnancy test on them,” Moffett said.

If Turco was correct, the miniature ball of cells she had created would secrete HCG, the hormone that triggers a positive pregnancy test. “I took the stick, put it in, and it was positive,” says Turco, now a reproductive biologist at the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland. “It was the best celebration.”

Scientists make organoids such as this by coaxing stem cells to grow in a jelly-like substance and to self-assemble into clumps of tissue. The typically hollow or solid balls of cells don’t look anything like real organs. But they do take on key aspects of the organ that they’re meant to represent — liver, brain, lung, or stomach, for instance.

The mini-organs have the advantage of being more realistic than a 2D cell culture — the conventional in vitro workhorses — because they behave more like tissue. The cells divide, differentiate, communicate, respond to their environment and, just like in a real organ, die. And, because they contain human cells, they can be more representative than many animal models. “Animals are good models in the generalities, but they start to fall down in the particulars,” says Linda Griffith, a biological engineer at the Massachusetts Institute of Technology in Cambridge.

Over the past decade, organoid research has exploded. Researchers have used them to study early brain development, test cancer therapies, and much more. And these 3D models stand to become even more crucial as US agencies, including the National Institutes of Health, the Food and Drug Administration, and the Environmental Protection Agency, aim to move away from animal testing.

Now, researchers are using organoids to study female reproduction, an area in which animal models can be especially limited. Lab mice, for example, don’t menstruate. And their placentas don’t develop in the same way as human placentas do. That challenge, along with a historical lack of funding for women’s health research, has left basic questions unanswered.

“I really see it as a powerful model to do science,” says Mirjana Kessler, a cell biologist at the Ludwig Maximilian University of Munich in Germany, who has developed an organoid that mimics the fallopian tube and a biobank of ovarian cancer organoids.

Organoids of the placenta, endometrium, ovary, and vagina could help to reveal how these organs function, and what happens when things go awry.

“There’s so much work to do to understand the normal biology,” Turco says.

The placenta invades

The placenta plays a key part in maternal health during pregnancy. Humans aren’t the only species that develops a placenta, but the “human placenta is quite different than most other species, even primates, actually, apart from apes”, says Moffett. Mice and humans, for example, both have placentas that invade the uterine lining, but the timing of development and the depth of invasion differ. Exactly what happens during the early days of placental development is still unclear, but problems at this stage can have serious consequences later.

One of the placenta’s first jobs is to create a link between the mother and the developing embryo. To do this, the placenta invades the spiral arteries that feed the uterus. The invasive cells open up the arteries, “essentially making a channel so that mom can provide what she needs through her blood supply”, says Victoria Roberts, a developmental biologist at the Oregon National Primate Research Center in Beaverton. (Nature recognizes that transgender men and non-binary people might have female reproductive organs and might become pregnant. ‘Mother’ is used in this article to reflect language used by the field.)

The process can be deadly if it goes wrong. If the placenta invades too deeply, a condition called placenta accreta, the expectant mother can lose too much blood during birth. And if the organ doesn’t invade deeply enough, then the fetus might not get enough nutrients to sustain its growth.

Shallow invasion can also impact the mother’s health. When the placenta doesn’t get enough blood, research suggests it can become inflamed and secrete harmful factors into the mother’s blood that trigger pre-eclampsia, a condition characterized by protein build-up in the blood and dangerously high blood pressure. Worldwide, 2–8% of pregnant people develop the condition. “It’s a very serious pregnancy complication that goes silent and undetected until very late into pregnancy,” says Quinton Smith, a chemical engineer at the University of California, Irvine. The only way to cure the condition is to deliver the baby, even if that means a preterm birth.

To better understand the condition, Smith, Turco, and other researchers are using organoids made of placental cells called trophoblasts to model the molecular processes involved. Turco is focused on the basic biology of how invasion is regulated, a process that seems to be controlled by both the fetus and the mother. “It’s got to be a compromise,” Moffett says. “It’s an absolute dialogue.”

That dialogue seems to be happening between the placenta and the uterine lining. As a case in point, when an embryo implants somewhere the lining doesn’t exist — on a scar left by a previous caesarean delivery or in a fallopian tube, for example — “there’s no control of the invasion at all”, Turco says.

Research suggests that immune cells called uterine natural killer cells have a key role in this conversation. The cells don’t kill but instead send out chemical signals that help to regulate the invasion of the uterine lining.

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https://static.scientificamerican.com/dam/m/5ca078555bcb44f3/original/cell_clusters_in_hydrogel.jpg?m=1758727886.358&w=900

Cell clusters that resemble the uterine lining grow with support cells in a synthetic hydrogel.  Juan Gnecco, Linda G. Griffith

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Click the link below for the complete article:

https://www.scientificamerican.com/article/lab-grown-organoids-could-transform-female-reproductive-medicine/?_gl=1*h9ai5m*_up*MQ..*_ga*NTczMjU0NjM3LjE3NTk5NjY1Mzg.*_ga_0P6ZGEWQVE*czE3NTk5NjY1MzYkbzEkZzAkdDE3NTk5NjY1MzYkajYwJGwwJGgw

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Man charged with starting Palisades fire that killed 12 people

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A 29-year-old man has been arrested and charged with igniting the fire that days later became the devastating Palisades blaze, which killed 12 people and destroyed more than 6,800 structures in one of the most destructive wildfires in Los Angeles history.

Jonathan Rinderknecht was arrested near his Florida residence on federal charges of destruction of property by means of fire, acting US attorney for the central district of California, Bill Essayli, announced on Wednesday. No motive was presented.

The investigators allege Rinderknecht maliciously started what became the Lachman fire, shortly after midnight on New Year’s Day in the Pacific Palisades. That fire smoldered underground for nearly a week before resurfacing on 7 January amid heavy winds, spreading rapidly to become the Palisades fire, investigators say.

The Bureau of Alcohol, Tobacco, Firearms, and Explosives (ATF) said a wide-ranging investigation it conducted in past months raked in more than 13,000 items of evidence, and included hundreds of interviews – some overseas – and more than 200 leads. Investigators also documented more than 300 ATF reports, including a 200-page report detailing the origin and cause of the investigation.

According to Essayli, Rinderknecht, who was a Palisades resident before relocating to Florida, had been working as an Uber driver on New Year’s Eve and returned to the Pacific Palisades after his evening shift. Two passengers told law enforcement he appeared “agitated and angry” that night, Essayli said.

After dropping off a passenger, according to the investigators, Rinderknecht parked his car and walked up a nearby trail, taking iPhone videos at a hilltop location while listening to a rap song whose music video included objects being set alight. He had reportedly listened to the song and watched its video repeatedly in the days before the fire.

Law enforcement officials identified and interviewed Rinderknecht on 24 January. During questioning, he allegedly lied about his location when he first saw the fire, claiming he was near the bottom of a hiking trail. However, geolocation data from his 911 call showed he was standing above the fire in a clearing merely 30ft from the blaze as it rapidly grew, prosecutors said.

Among the digital evidence collected was an image Rinderknecht had generated on ChatGPT months before the fire, depicting what Essayli described as “a dystopian painting showing in part a burning forest and a crowd fleeing from it”.

The Palisades fire was one of several major blazes that encircled Los Angeles in early January. The blaze destroyed more than 6,800 structures, including homes and businesses, and damaged over 1,000 more buildings. A fire that broke out the same day in nearby Altadena killed nearly 20 people. Investigators have not yet determined the cause of that fire.

Rinderknecht faces a mandatory minimum five-year federal prison sentence if convicted, with a maximum penalty of up to 20 years. He was scheduled to make his initial appearance on Wednesday afternoon in federal court in Orlando, Florida.

“While we cannot undo the damage and destruction that was done, we hope his arrest and the charges against him bring some measure of justice to the victims of this horrific tragedy,” Essayli said.

In a statement, California Governor Gavin Newsom thanked investigators for “confirming the indisputable facts on the ground”.

“Today’s arrest of 29-year-old Florida resident Jonathan Rinderknecht marks an important step toward uncovering how the horrific Palisades fire began and bringing closure to the thousands of Californians whose lives were upended,” he said.

An outside review of Los Angeles county’s response to the blazes released last month found that critical staffing shortages, including at sheriff’s department and the office of emergency management, contributed to the emergency. The report also concluded that outdated policies for sending emergency alerts led to delays in warning residents about the need to evacuate as flames began consuming neighborhoods in Altadena and the Pacific Palisades. In addition, the report noted, information sharing between emergency responders was hampered by unreliable cellular connectivity, inconsistent field reporting methods, and the use of different communicating platforms.

The report was produced by the consulting firm McChrystal Group and was commissioned by county supervisors.

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debris on the groundAn aerial view of homes which were destroyed in the Palisades fire, with some lots cleared of debris on 15 March 2025 in Pacific Palisades, California. Photograph: Mario Tama/Getty Images

a man looking at a camera

Jonathan Rinderknecht, a suspect in the Palisades fire. Photograph: AP

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Click the link below for the complete article:

https://www.theguardian.com/us-news/2025/oct/08/palisades-fire-florida-arrest

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Alone During a Heart Attack? Here’s How to Survive Until Help Arrives

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A heart attack happens when there is a buildup of cholesterol and fat, which leads to the formation of plaque in your arteries that provide blood flow to the heart. The plaque formation not only disrupts the blood flow but also damages the heart muscle. Doctors say that most heart attacks happen when people are alone, which makes them dangerous and life-threatening.

Hence, it is important to know what to do when the symptoms of a heart attack come on to save your life.

Experts say it is important to be prepared through proper awareness to save your life. It is also important to recognize the symptoms that could signal a possible heart attack.

  • Acute or heavy pain in the chest
  • Pain continuing in the arms, especially the left arm, neck, jaws, and back
  • Difficulty in breathing
  • Intense fatigue
  • Nausea and Vomiting
  • Excessive sweat

Doctors advise never to take these symptoms lightly, especially when you are living alone. Also, women may experience different symptoms, like sharp pain in their neck, arm, or back. In some cases, the first sign of a heart attack can also be sudden cardiac arrest – a medical condition where the heart stops beating unexpectedly and can be dangerous if the treatment is delayed.

Sometimes, heart attacks do not happen suddenly. Many people have warning signs hours, days, or even weeks before. Persistent chest pain or pressure that does not go away with rest could be an early warning sign of a heart attack.

What should you do in case of a heart attack?

Being alone during a medical emergency like a heart attack can be a scary experience, and so it is important to make the right moves to survive till help arrives. While you may not be able to stop a heart attack alone, prompt medical help can prevent further severe damage. Here is a list of steps to follow on how to survive a heart attack when alone:

Call emergency services immediately

Immediately dial 108 or the local emergency number. Inform the operator of the condition and follow their instructions.

Take an aspirin

Take a tablet, chew and swallow it as soon as you begin feeling symptoms of a heart attack. Doctors say the medicines thin your blood, which alleviates the severity of a heart attack.

Take rest

You must immediately sit down in a comfortable position and, if feeling lightheaded or dizzy, lie on the left side of your body with legs bent. According to experts, this position helps improve blood flow to the heart

Call someone

Until the ambulance or doctor arrives, immediately call a friend, family member, or neighbour who can provide comfort and assistance

Stay calm

Experts suggest taking long and steady breaths to help stay calm. Do not panic and remember that help is on its way.

Do not eat or drink anything.

Do not attempt to eat or drink anything, as this might complicate the situation.

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https://img-s-msn-com.akamaized.net/tenant/amp/entityid/AA1O3cRo.img?w=768&h=432&m=6&x=565&y=131&s=104&d=104Alone during a heart attack? Here’s how to survive until help arrives

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Click the link below for the complete article:

https://www.msn.com/en-ca/health/other/alone-during-a-heart-attack-here-s-how-to-survive-until-help-arrives/ar-AA1O3hXm?ocid=hpmsn&cvid=68e6fa97fff8435fbf280d5cef5c9a9d&ei=27

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