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Gene Editing Spurs Hope for Transplanting Pig Organs Into Humans

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In a striking advance that helps open the door to organ transplants from animals, researchers have created gene-edited piglets cleansed of viruses that might cause disease in humans.

The experiments, reported on Thursday in the journal Science, may make it possible one day to transplant livers, hearts and other organs from pigs into humans, a hope that experts had all but given up.

If pig organs were shown to be safe and effective, “they could be a real game changer,” said Dr. David Klassen, chief medical officer at the United Network for Organ Sharing, a private, nonprofit organization that manages the nation’s transplant system.

There were 33,600 organ transplants last year, and 116,800 patients on waiting lists, according to Dr. Klassen, who was not involved in the new study. “There’s a big gap between organ supply and organ demand,” he said.

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 Piglets whose genes were edited to remove retroviruses, which could help clear the way for pig organs to be transplanted to humans. Credit eGenesis

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Click link below for article:

https://www.nytimes.com

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Introducing the man who could be the most vulnerable Republican in Congress

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Mike Coffman has survived tough races before. But Trump will make things much harder.

Shortly before Paul Rodkin encouraged me to pursue a job at Fox News, he vigorously defended President Donald Trump’s tumultuous first six months in the White House.
“Trump can do no wrong in my eyes,” the 70-year-old Centennial, Colorado, resident who used to run a granite slab company told me. The constant upheaval in Washington, he said, was to be expected at the outset of Trump’s administration.
“When he gets rid of all these people in the swamp, then it will prove that he means business,” Rodkin said.

As we stood in the parking lot of SouthGlenn Mall, Rodkin described himself as an “extremely conservative Sean Hannity Republican” and expressed disdain for the media and Republicans in Congress, chiding them for pursuing Medicaid cuts. His loyalty lies with Trump – not House Speaker Paul Ryan or Senate Majority Leader Mitch McConnell, both of whom “need to go,” Rodkin said.

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Aurora, Colorado

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Click link below for article:

http://www.cnn.com/interactive/2017/politics/state/midterms-colorado-sixth-district-mike-coffman/

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Day care driver expected to face charges after boy found dead in van

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A Florida day care center employee is expected to face charges after a 3-year-old boy was found dead in a parked van, police in Orlando said Tuesday.

Myles Hill was found on the floor at the back of the van parked at the Little Miracles Academy day care center around 6:30 p.m. on Monday, police told reporters. Police Chief John Mina said authorities believe he had been in the vehicle since around 9 a.m. that morning. The high temperature in Orlando on Monday was about 93 degrees Fahrenheit, according to Weather Underground.
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The cause of Myles’ death has not been determined, but Mina said that based on the evidence, it is believed to be heat-related. “This was an absolute tragedy that could have been prevented,” Mina told reporters on Tuesday.

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Your car can be deadly, even when parked

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Click link below for article and video:

http://www.cnn.com/2017/08/08/us/orlando-day-care-van-death/index.html

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Here, heroin spares no one, not even the sheriff’s wife

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Robert Leahy was sitting on his couch, watching TV, when his wife, Gretchen, walked through the front door.

It was about 10 p.m. She’d left for the grocery store hours earlier. Now, she “bumbled” about the room, Leahy says, incoherent and vacant. He’d seen her like this before.
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“What the f**k are you doing?” he asked. “You’re high.”
  
After the initial shock wore off, Leahy was angry and embarrassed. He worried about his reputation and what his colleagues at the Clermont County Sheriff’s Office would think. He’d been a law enforcement officer for more than a decade, and now he was married to a heroin addict.
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He needed to save himself and their young son. He had done all he could to save her.

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It’s ‘chemical warfare’ on our children

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Click link below for article and video:

http://www.cnn.com/2017/08/06/health/ohio-heroin-opioid-crisis-morgue-full/index.html

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The Trigger and the Choice – Part 3

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Part 3: The officers of the Buffalo Police Department went more than four years and 2 million calls without a fatal shooting. What did they do right?

This city gets heavy snow in the winter, hard rain in the summer, and the occasional gun falling from the sky. Maybe it clatters onto a roof, or clangs into a garbage can, or splashes down in an open field. Wherever it falls, two men may come looking for it: Officers Mark Hamilton and Michael Acquino, who confiscate more illegal guns than any other pair in the Buffalo Police Department.

These transactions often start on the sidewalk, when someone acts just a little off: talking too fast, volunteering too much information, pretending to be on the phone, and maybe they reach for the waistband, and maybe they start to run. This is when the evidence goes airborne. The average loaded handgun weighs about two pounds, roughly six times as much as a baseball. You’d be surprised how far a man on parole can make one fly.

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The Trigger And the Choice Part 3

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Click link below for article:

http://www.cnn.com/interactive/2017/politics/state/buffalo-police-shooting/

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B-1 Bombers Key to a U.S. Plan to Strike North Korean Missile Sites

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The Pentagon has prepared a specific plan for a preemptive strike on North Korea’s missile sites should President Trump order such an attack.

Two senior military officials — and two senior retired officers — told NBC News that key to the plan would be a B-1B heavy bomber attack originating from Andersen Air Force Base in Guam.

Pairs of B-1s have conducted 11 practice runs of a similar mission since the end of May, the last taking place on Monday. The training has accelerated since May, according to officials. In an actual mission, the non-nuclear bombers would be supported by satellites and drones and surrounded by fighter jets as well as aerial refueling and electronic warfare planes.

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Image: US Air Force B-1B Lancers A US Air Force B-1B Lancer assigned to the 37th Expeditionary Bomb Squadron, deployed from Ellsworth Air Force Base, South Dakota, USA during a 10-hour mission from Andersen Air Force Base, Guam. US Air Force / EPA

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Click link below for article and videos:

http://www.nbcnews.com/news/north-korea/b-1-bombers-key-u-s-plan-strike-north-korean-n791221

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Manafort’s Home Searched as Part of Mueller Inquiry

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Investigators for the special counsel, Robert S. Mueller III, recently searched the Northern Virginia home of President Trump’s former campaign manager, Paul Manafort, for tax documents and foreign banking records, a sign that the inquiry into Mr. Manafort has broadened, according to a person familiar with the matter.

The search was carried out at Mr. Manafort’s Alexandria, Va., home shortly after Mr. Manafort met with investigators for the Senate Intelligence Committee on July 25. In that meeting, Mr. Manafort answered questions and provided investigators with notes from a 2016 meeting between Trump campaign officials and Russians claiming to have damaging information on Hillary Clinton.

Mr. Manafort’s spokesman confirmed that an F.B.I. raid had been carried out.

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 Paul Manafort, President Trump’s former campaign manager, at the Republican National Convention in Cleveland last July. Credit Rick Wilking/Reuters

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Click link below for article:

https://www.nytimes.com

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Mattis to North Korea: Stop actions that could lead to ‘destruction of its people’

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US Defense Secretary James Mattis issued a dramatic ultimatum to North Korea on Wednesday to “cease any consideration of actions that would lead to the end of its regime and destruction of its people” — strong words that come just one day after President Donald Trump warned that the US could unleash “fire and fury” on Pyongyang.

“The DPRK must choose to stop isolating itself and stand down its pursuit of nuclear weapons,” Mattis said in a written statement, adding that the “regime’s actions will continue to be grossly overmatched by ours and would lose any arms race or conflict it initiates.”
Mattis has consistently said that he prefers to resolve issues over North Korea’s missile and nuclear programs through diplomacy — noting military action could yield catastrophic consequences.

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James Mattis

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Click link below for article and video:

http://www.cnn.com/2017/08/09/politics/mattis-pentagon-north-korea/index.html

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Glen Campbell, clean-cut country star and crossover hitmaker, dies at 81

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Glen Campbell, a guitar prodigy and ballad singer who dominated the polished, string-swelling countrypolitan sound of the late 1960s and 1970s and cultivated a clean-cut image at odds with his once-stormy personal life, died Aug. 8 in Nashville. He was 81.

His publicist confirmed the death to the Associated Press. Mr. Campbell announced that he had Alzheimer’s disease in 2011 and performed what he called the Glen Campbell Goodbye Tour shortly thereafter. In 2015, he won his sixth and final Grammy Award, honored for best country song “I’m Not Gonna Miss You,” which he co-wrote for a documentary about his life and deteriorating health.

In a career that spanned six decades, Mr. Campbell made dozens of albums, sold more than 40 million records and was inducted into the Country Music Hall of Fame. At a time when the grittier “outlaw” movement of Waylon Jennings and Willie Nelson was on the rise, Mr. Campbell vaulted to fame as an unabashed sentimentalist whose songs were aimed squarely at the American heartland.

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Country music star Glen Campbell died Aug. 8 at the age of 81. In June 2011, Campbell announced that he had been diagnosed with Alzheimer’s disease. (The Washington Post)

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Click link below for article and videos:

 

Country singing star Glen Campbell dies at 81

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America’s greatest eclipse is coming, and this man wants you to see it

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He approaches the first stranger with an expectant smile and an urgent query: “Do you know about the solar eclipse?”

The man shakes his head, and Mike Kentrianakis is launched. He’s here at the Hayden Planetarium as an emissary of the American Astronomical Society, and his mission is to spread the word: On Aug. 21, the moon will pass between the sun and Earth, casting a shadow across a swath of the United States. The spectacle will be like nothing most people have ever seen.

Carmen Irizarry, a science teacher from Staten Island, walks over with her two young granddaughters. She’s been thinking about taking them to a spot on the path of totality — where the moon will completely block out the sun for a few mesmerizing minutes. “I entirely encourage it,” Kentrianakis tells her. “It’s a completely different phenomenon. It shouldn’t even be called an eclipse. It should be called something else.”

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Total eclipse this August

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Click link below for article and video:

America’s greatest eclipse is coming, and this man wants you to see it …

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