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Seven years ago, scientists at Illumina, the DNA sequencing company in San Diego, were running a study seeking DNA fragments in pregnant people’s blood that might suggest chromosomal abnormalities.
During the research, a pathologist discovered something unexpected in 10 of the blood samples.
Instead of chromosomal disorders, the testing showed DNA abnormalities.
This didn’t make sense to the researchers. But there was some suspicion that cancer was involved.
Investigating further, the researchers learned that one of the 10 participants had in fact received a cancer diagnosis, and others in that subset also had cancer — despite the fact that they had no symptoms.
This convinced Illumina’s leadership to create a spin-off company in 2016 called GRAIL that combined advances in human genomics with machine learning data science.
That resulted in the development of a new blood test from GRAIL called Galleri, which can detect early stages of cancer before a person has symptoms.
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Galleri is a new blood test that has the ability to detect 50 types of cancer through a single blood draw. Select U.S. health systems will begin using it this year. Daniel Balakov/Getty Images
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