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Tiny versions of human organs smaller than a pea are making a big splash around the world — and for a good reason. Though the clusters of cells of brain, kidney, or liver aren’t much to look at, experts say these so-called “organoids” and “organs-on-a-chip” are poised to remake the way new drugs are brought to market.
Right now, drug development is notoriously slow and costly; bringing a new drug to market can take a dozen years and cost upward of $2 billion. Even after all that time and money have been spent, new drug candidates often prove to be ineffective — or to have dangerous side effects.
“A huge percentage of drugs fail even after hundreds of millions or billions of dollars of investment,” says Dr. Donald Ingber, director of Harvard University’s Wyss Institute for Biologically Inspired Engineering and a leader in organ-on-a-chip technology. In fact, only about one in 10 drugs that make it to human tests (after testing in the lab and in animals) wind up getting FDA approval.
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Click link below for article:
https://www.nbcnews.com/mach/science/tiny-organoids-promise-big-boost-medical-care-ncna793986
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