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The Challenge: Can you figure out what is wrong with a 58-year-old woman with bad arthritis who develops a terrible wasting illness after what looked like a simple cold?

Every month, the Diagnosis column of The New York Times Magazine asks Well readers to try to figure out a real-life diagnostic mystery. Below you will find the details of a case involving a middle-age woman with terrible arthritis who catches a cold that seems to turn into something much worse. Over the course of just a few months she loses 30 pounds and much of her strength. Can you figure out why?

The final diagnosis was surprising to almost everyone involved. Below, I provide most of the records that were available when the diagnosis was made. As usual, the first person to solve the case gets a signed copy of my book “Every Patient Tells…

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