Previously the older anti-depressants were notorious for triggering or precipitating (hypo)manic episodes in Bipolar patients, newer antidepressants such as SSRIs, bupropion and venlafaxine, do not appear as likely to precipitate mania. Both the mood stabilisers lamotrigine (Lamictal) and Topiramate (Topamax) don’t carry a risk of inducing mania. In the DSM-IV and DSM-V (Diagnostic and Statistical Manual of Mental Disorders) stipulates that diagnosing a person with Bipolar Disorder has to fit these criteria:
Criteria F: The episode is not attributable to the physiological effects of a substance (e.g. a drug of abuse, a medication, other treatment).
Note: A full hypomanic episode that emerges during antidepressant treatment (e.g. medication, electroconvulsive therapy) but persists at a fully syndromal level beyond the physiological effect of that treatment is sufficient evidence of a hypomanic episode diagnosis(My note: most* antidepressants other than Prozac are out of your system in a week). However, caution is…
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James' World 2 
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